World Chagas Disease Day, established by the United Nations in 2020, serves as a platform to raise awareness about Chagas Disease, often referred to as the “silent or silenced disease.” This illness disproportionately affects marginalized communities who lack access to adequate healthcare and political representation. Notably, Chagas Disease progresses slowly and is frequently asymptomatic, leading to challenges in early detection and treatment. Without intervention, it can result in severe cardiac and digestive complications. By highlighting the impact of Chagas Disease, this day aims to advocate for increased resources, research, and support for affected individuals and communities globally.